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Nurse Practitioners Salary in Missouri

Nurse Practitioners in Missouri earn a median $129,930 a year, 2% below the U.S. median.

Median in MO
$129,930 a year
U.S. median
$132,300 a year
Employment
7,710
Location quotient
1.26
Share of jobs vs. U.S. (1.00 = same)

Pay range in Missouri

10%: $100,650Median: $129,93090%: $162,060
Median (50%)
$129,930 · $62.47 an hour
Mean (average)
$130,970 · $62.97 an hour (estimate error ±1.0%)
10th percentile
$100,650 · $48.39 an hour
25th percentile
$119,910 · $57.65 an hour
75th percentile
$144,640 · $69.54 an hour
90th percentile
$162,060 · $77.91 an hour
Employment
7,710 (estimate error ±7.4%)
Jobs per 1,000
2.63
Location quotient
1.26 (1.00 = national share)

Nurse Practitioners pay by metro area in Missouri

Includes metro areas that cross into this state and nonmetropolitan areas

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Frequently asked questions

How much do nurse practitioners make in Missouri?
The median wage for nurse practitioners in Missouri is $129,930 a year (Bureau of Labor Statistics, May 2025). There are about 7,710 jobs in the state.
Where in Missouri do nurse practitioners earn the most?
St. Louis, MO-IL has the highest median wage in the state for this occupation at $131,580 a year.