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Registered Nurses Salary in Missouri
Registered Nurses in Missouri earn a median $81,780 a year, 16% below the U.S. median.
- Median in MO
- $81,780 a year
- U.S. median
- $97,550 a year
- Employment
- 76,310
- Location quotient
- 1.20
- Share of jobs vs. U.S. (1.00 = same)
Pay range in Missouri
- Median (50%)
- $81,780 · $39.32 an hour
- Mean (average)
- $85,900 · $41.30 an hour (estimate error ±0.3%)
- 10th percentile
- $63,230 · $30.40 an hour
- 25th percentile
- $76,050 · $36.56 an hour
- 75th percentile
- $98,560 · $47.39 an hour
- 90th percentile
- $104,390 · $50.19 an hour
- Employment
- 76,310 (estimate error ±1.0%)
- Jobs per 1,000
- 25.99
- Location quotient
- 1.20 (1.00 = national share)
Registered Nurses pay by metro area in Missouri
Includes metro areas that cross into this state and nonmetropolitan areas
Swipe the table sideways to see more columns.
| Area | Median wage | Employment |
|---|---|---|
| Jefferson City, MO | $85,010 | 1,910 |
| Columbia, MO | $84,330 | 3,680 |
| St. Louis, MO-IL | $83,180 | 35,200 |
| Kansas City, MO-KS | $83,040 | 29,650 |
| Cape Girardeau, MO-IL | $82,640 | 1,470 |
| Southwest Missouri nonmetropolitan area | $79,660 | 1,270 |
| Springfield, MO | $79,370 | 6,820 |
| Central Missouri nonmetropolitan area | $78,810 | 2,800 |
| North Missouri nonmetropolitan area | $78,230 | 2,020 |
| St. Joseph, MO-KS | $77,240 | 1,490 |
| Southeast Missouri nonmetropolitan area | $77,220 | 3,650 |
| Joplin, MO-KS | $74,930 | 2,670 |
H-1B filings for registered nurses in Missouri
FY 2026 through Q3, by work location
11 certified filings with a median offered wage of $68,000.
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Frequently asked questions
- How much do registered nurses make in Missouri?
- The median wage for registered nurses in Missouri is $81,780 a year (Bureau of Labor Statistics, May 2025). There are about 76,310 jobs in the state.
- Where in Missouri do registered nurses earn the most?
- Jefferson City, MO has the highest median wage in the state for this occupation at $85,010 a year.